GSK894281

Modify Date: 2025-10-11 12:36:08

GSK894281 Structure
GSK894281 structure
 Common Name GSK894281
CAS Number 874958-63-1 Molecular Weight 473.56000
Density N/A Boiling Point N/A
Molecular Formula C24H28FN3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK894281


GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1].

 Names

Name N-[5-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl]-3-fluoro-4-(5-methylfuran-2-yl)benzenesulfonamide
Synonym More Synonyms

 GSK894281 Biological Activity

Description GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1].
Related Catalog
References

[1]. A D Shafton, et al.Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation. Neurogastroenterol Motil. 2009 Jan;21(1):71-7.  

 Chemical & Physical Properties

Molecular Formula C24H28FN3O4S
Molecular Weight 473.56000
Exact Mass 473.17800
PSA 92.19000
LogP 5.93770

 Synonyms

unii-dhj6673as1
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Chemsrc provides GSK894281(CAS#:874958-63-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of GSK894281 are included as well.>> amp version: GSK894281

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