874958-63-1

874958-63-1 structure

Name: GSK894281
Chemical Name: N-[5-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl]-3-fluoro-4-(5-methylfuran-2-yl)benzenesulfonamide
CAS Number: 874958-63-1
Molecular Formula: C₂₄H₂₈FN₃O₄S
Molecular Weight: 473.56000
Catalog: Signaling Pathways GPCR/G Protein GHSR
Create Date: 2017-04-28 13:27:18
Modify Date: 2025-10-11 12:36:08
GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1].

Name	N-[5-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl]-3-fluoro-4-(5-methylfuran-2-yl)benzenesulfonamide
Synonyms	unii-dhj6673as1

Description	GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> GHSR
References	[1]. A D Shafton, et al.Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation. Neurogastroenterol Motil. 2009 Jan;21(1):71-7.