GSK894281

Names

[ Name ]:
GSK894281

[Synonym ]:
unii-dhj6673as1

Biological Activity

[Description]:

GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> GHSR

[References]

[1]. A D Shafton, et al.Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation. Neurogastroenterol Motil. 2009 Jan;21(1):71-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₈FN₃O₄S

[ Molecular Weight ]:
473.56000

[ Exact Mass ]:
473.17800

[ PSA ]:
92.19000

[ LogP ]:
5.93770

Related Compounds

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