Dipraglurant

Modify Date: 2025-09-21 13:41:47

Dipraglurant structure	Common Name	Dipraglurant
	CAS Number	872363-17-2	Molecular Weight	265.28500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₂FN₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dipraglurant

Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. IC50 Value: 0.021 μM [1]Target: mGluRDipraglurant (ADX-48621) from Addex Therapeutics showed in vivo activity in different anxiety models in rat50 and is currently in phase II for the treatment of dyskinesia in Parkinson's disease.

Name	6-fluoro-2-(4-pyridin-2-ylbut-3-ynyl)imidazo[1,2-a]pyridine
Synonym	More Synonyms

Description	Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. IC50 Value: 0.021 μM [1]Target: mGluRDipraglurant (ADX-48621) from Addex Therapeutics showed in vivo activity in different anxiety models in rat50 and is currently in phase II for the treatment of dyskinesia in Parkinson's disease.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
References	[1]. The Synthesis and Use of Certain Pyridine Derivatives as Modulators of the G-protein Coupled Receptors mGlu5 and P2Y12

Molecular Formula	C₁₆H₁₂FN₃
Molecular Weight	265.28500
Exact Mass	265.10200
PSA	30.19000
LogP	2.85270

Dipraglurant

CS-0690

Dipraglurant [INN]

UNII-CV8JZR21A1

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China
Product Name: Dipraglurant
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China
Product Name: Dipraglurant
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Price: $490/10mM*1mLinDMSO

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Dipraglurant

Use of Dipraglurant

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Dipraglurant Biological Activity

Chemical & Physical Properties

Synonyms

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