NSCI
Modify Date: 2025-09-25 19:39:57
NSCI structure
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Common Name | NSCI | ||
|---|---|---|---|---|
| CAS Number | 872254-32-5 | Molecular Weight | 507.55800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H25N3O6S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of NSCICaspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1]. |
| Name | 1-[(4-methoxyphenyl)methyl]-5-[(2S)-2-(pyridin-3-yloxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione |
|---|---|
| Synonym | More Synonyms |
| Description | Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1]. |
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| Related Catalog | |
| Target |
Caspase-3:14.5 ± 1.6 nM (IC50) Caspase-7:21.8 ± 3.5 nM (IC50) Caspase-6:>5000 nM (IC50) Caspase-1:>10000 nM (IC50) Caspase-8:>50000 nM (IC50) |
| References |
| Molecular Formula | C26H25N3O6S |
|---|---|
| Molecular Weight | 507.55800 |
| Exact Mass | 507.14600 |
| PSA | 114.49000 |
| LogP | 4.13550 |
| RIDADR | NONH for all modes of transport |
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Structural insight on the control of urea synthesis: identification of the binding site for N-acetyl-L-glutamate, the essential allosteric activator of mitochondrial carbamoyl phosphate synthetase.
Biochem. J. 424 , 211-20, (2009) NAG (N-acetyl-L-glutamate), the essential allosteric activator of the first urea cycle enzyme, CPSI (carbamoyl phosphate synthetase I), is a key regulator of this crucial cycle for ammonia detoxificat... |
| Pyridine Analogue 21c |