TC-S 7006 structure
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Common Name | TC-S 7006 | ||
|---|---|---|---|---|
| CAS Number | 871307-18-5 | Molecular Weight | 404.82700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H14ClFN6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TC-S 7006Tpl2 Kinase Inhibitor 1 (Compound 1) is a potent and selective Tpl2 (COT kinase, MAP3K8) inhibitor, plays an important role in the regulation of the inflammatory response and the progression of some cancers[1]. |
| Name | 4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile |
|---|---|
| Synonym | More Synonyms |
| Description | Tpl2 Kinase Inhibitor 1 (Compound 1) is a potent and selective Tpl2 (COT kinase, MAP3K8) inhibitor, plays an important role in the regulation of the inflammatory response and the progression of some cancers[1]. |
|---|---|
| Related Catalog | |
| Target |
MAP3K8 |
| In Vitro | Cancer Osaka thyroid (COT) kinase (Tpl2) is an important regulator of pro-inflammatory cytokines in macrophages[1]. |
| References |
| Molecular Formula | C21H14ClFN6 |
|---|---|
| Molecular Weight | 404.82700 |
| Exact Mass | 404.09500 |
| PSA | 86.52000 |
| LogP | 5.19068 |
| InChIKey | NMEUKWOOQOHUNA-UHFFFAOYSA-N |
| SMILES | N#Cc1cnc2cnc(NCc3cccnc3)cc2c1Nc1ccc(F)c(Cl)c1 |
| HS Code | 2933990090 |
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| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 4-((3-Chloro-4-fluorophenyl)amino)-6-((pyridin-3-ylmethyl)amino)-1,7-naphthyridine-3-carbonitrile |
| Tpl2 Kinase Inhibitor |
| 4-[(3-CHLORO-4-FLUOROPHENYL)AMINO]-6-[(3-PYRIDINYLMETHYL)AMINO]-1,7-NAPHTHYRIDINE-3-CARBONITRILE |
| 4-(3-Chloro-4-fluorophenylamino)-6-(pyridin-3-yl-methylamino)-3-cyano-[1,7]-naphthyridine |