GQ-16
Modify Date: 2025-08-25 19:18:19
GQ-16 structure
|
Common Name | GQ-16 | ||
|---|---|---|---|---|
| CAS Number | 870554-67-9 | Molecular Weight | 418.304 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 549.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C19H16BrNO3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 286.3±32.9 °C | |
Use of GQ-16GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARγ, exhibiting a Ki of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPARγ. GQ-16 is a partial agonist of PPARγ with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain[1]. |
| Name | gq-16 |
|---|---|
| Synonym | More Synonyms |
| Description | GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARγ, exhibiting a Ki of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPARγ. GQ-16 is a partial agonist of PPARγ with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 549.8±60.0 °C at 760 mmHg |
| Molecular Formula | C19H16BrNO3S |
| Molecular Weight | 418.304 |
| Flash Point | 286.3±32.9 °C |
| Exact Mass | 417.003418 |
| PSA | 71.91000 |
| LogP | 5.79 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.688 |
| InChIKey | AMLZLORVKZAHOH-YVLHZVERSA-N |
| SMILES | COc1ccc(Br)cc1C=C1SC(=O)N(Cc2ccc(C)cc2)C1=O |
| (5Z)-5-(5-Bromo-2-methoxybenzylidene)-3-(4-methylbenzyl)-1,3-thiazolidine-2,4-dione |
| 2,4-Thiazolidinedione, 5-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-, (5Z)- |