Benzyl-PEG6-amine

Modify Date: 2024-01-14 18:19:20

Benzyl-PEG6-amine Structure
Benzyl-PEG6-amine structure
Common Name Benzyl-PEG6-amine
CAS Number 86770-78-7 Molecular Weight 371.47
Density N/A Boiling Point N/A
Molecular Formula C19H33NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyl-PEG6-amine


Benzyl-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Benzyl-PEG6-amine

 Benzyl-PEG6-amine Biological Activity

Description Benzyl-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H33NO6
Molecular Weight 371.47