1-Phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl methanesulfonate

Modify Date: 2024-04-06 07:51:26

1-Phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl methanesulfonate Structure
1-Phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl methanesulfonate structure
Common Name 1-Phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl methanesulfonate
CAS Number 1262681-32-2 Molecular Weight 450.54
Density N/A Boiling Point N/A
Molecular Formula C20H34O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-Phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl methanesulfonate


Benzyl-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Benzyl-PEG6-MS

  Biological Activity

Description Benzyl-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C20H34O9S
Molecular Weight 450.54