Fostemsavir Tris
Modify Date: 2025-09-11 12:31:00
Fostemsavir Tris structure
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Common Name | Fostemsavir Tris | ||
|---|---|---|---|---|
| CAS Number | 864953-39-9 | Molecular Weight | 704.625 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H37N8O11P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Fostemsavir TrisFostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. |
| Name | BMS-663068 Tris |
|---|---|
| Synonym | More Synonyms |
| Description | Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. |
|---|---|
| Related Catalog | |
| Target |
HIV-1[1] |
| In Vivo | Fostemsavir Tris has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent[1]. |
| References |
| Molecular Formula | C29H37N8O11P |
|---|---|
| Molecular Weight | 704.625 |
| Exact Mass | 704.231934 |
| InChIKey | RRGJSMBMTOKHTE-UHFFFAOYSA-N |
| SMILES | COc1cnc(-n2cnc(C)n2)c2c1c(C(=O)C(=O)N1CCN(C(=O)c3ccccc3)CC1)cn2COP(=O)(O)O.NC(CO)(CO)CO |
| Fostemsavir tromethamine |
| 1,2-Ethanedione, 1-(4-benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) |
| BMS-663068-03 |
| {3-[(4-Benzoyl-1-piperazinyl)(oxo)acetyl]-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl}methyl dihydrogen phosphate - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) |
| 2X513P36U0 |
| MFCD23098797 |
| BMS-663068 (Tris) |