Mildronate
Modify Date: 2025-08-20 17:28:18
Mildronate structure
|
Common Name | Mildronate | ||
|---|---|---|---|---|
| CAS Number | 86426-17-7 | Molecular Weight | 182.218 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C6H18N2O4 | Melting Point | N/A | |
| MSDS | Chinese | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of MildronateMildronate dihydrate (Meldonium dihydrate) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1]. |
| Name | Mildronate dihydrate |
|---|---|
| Synonym | More Synonyms |
| Description | Mildronate dihydrate (Meldonium dihydrate) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 34-62 μM (human recombinant BBOX). EC50: 21 μM (human OCTN2). |
| References |
| Molecular Formula | C6H18N2O4 |
|---|---|
| Molecular Weight | 182.218 |
| Exact Mass | 182.126663 |
| PSA | 70.62000 |
| Appearance of Characters | white to off-white |
| Storage condition | 2-8°C |
| Water Solubility | H2O: >40mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
|
A rapid method for determination of 22 selected drugs in human urine by UHPLC/MS/MS for clinical application.
J. AOAC Int. 97(6) , 1526-37, (2015) A rapid and sensitive ultra-HPLC/MSIMS (UHPLC/MSIMS) assay method for the simultaneous determination in human urine of 22 drugs belonging to different pharmaceutical groups was developed. The drugs we... |
| 3-(2,2,2-Trimethylhydrazinium)propionate dihydrate |
| Diazanium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt, hydrate (1:2) |
| Mildronatedehydrate |
| 3-(2,2,2-Trimethyldiazan-2-ium-1-yl)propanoate dihydrate |
| Mildronate |