Mildronate structure
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Common Name | Mildronate | ||
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CAS Number | 86426-17-7 | Molecular Weight | 182.218 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C6H18N2O4 | Melting Point | N/A | |
MSDS | Chinese | Flash Point | N/A | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of MildronateMildronate dihydrate (Meldonium dihydrate) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1]. |
Name | Mildronate dihydrate |
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Synonym | More Synonyms |
Description | Mildronate dihydrate (Meldonium dihydrate) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1]. |
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Related Catalog | |
Target |
IC50: 34-62 μM (human recombinant BBOX). EC50: 21 μM (human OCTN2). |
References |
Molecular Formula | C6H18N2O4 |
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Molecular Weight | 182.218 |
Exact Mass | 182.126663 |
PSA | 70.62000 |
Appearance of Characters | white to off-white |
Storage condition | 2-8°C |
Water Solubility | H2O: >40mg/mL |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Phrases | 36/37/38 |
Safety Phrases | 26 |
RIDADR | NONH for all modes of transport |
A rapid method for determination of 22 selected drugs in human urine by UHPLC/MS/MS for clinical application.
J. AOAC Int. 97(6) , 1526-37, (2015) A rapid and sensitive ultra-HPLC/MSIMS (UHPLC/MSIMS) assay method for the simultaneous determination in human urine of 22 drugs belonging to different pharmaceutical groups was developed. The drugs we... |
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