MMAF intermediate 2
Modify Date: 2025-08-25 17:38:59
MMAF intermediate 2 structure
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Common Name | MMAF intermediate 2 | ||
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| CAS Number | 864238-20-0 | Molecular Weight | 384.898 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H29ClN2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MMAF intermediate 2MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1]. |
| Name | L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) |
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| Synonym | More Synonyms |
| Description | MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1]. |
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| Related Catalog | |
| References |
[1]. |
| Molecular Formula | C19H29ClN2O4 |
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| Molecular Weight | 384.898 |
| Exact Mass | 384.181580 |
| Methyl N-{(2R,3R)-3-methoxy-2-methyl-3-[(2S)-2-pyrrolidinyl]propanoyl}-L-phenylalaninate hydrochloride (1:1) |
| L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-[(2S)-2-pyrrolidinyl]propyl]-, methyl ester, hydrochloride (1:1) |