864238-20-0
864238-20-0 structure
- Name: MMAF intermediate 2
- Chemical Name: L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI)
- CAS Number: 864238-20-0
- Molecular Formula: C19H29ClN2O4
- Molecular Weight: 384.898
- Catalog: Research Areas Cancer
- Create Date: 2018-10-16 13:05:20
- Modify Date: 2025-08-25 17:38:59
-
MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1].
| Name | L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-(2S)-2-pyrrolidinylpropyl]-, methyl ester, monohydrochloride (9CI) |
|---|---|
| Synonyms |
Methyl N-{(2R,3R)-3-methoxy-2-methyl-3-[(2S)-2-pyrrolidinyl]propanoyl}-L-phenylalaninate hydrochloride (1:1)
L-Phenylalanine, N-[(2R,3R)-3-methoxy-2-methyl-1-oxo-3-[(2S)-2-pyrrolidinyl]propyl]-, methyl ester, hydrochloride (1:1) |
| Description | MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. |
| Molecular Formula | C19H29ClN2O4 |
|---|---|
| Molecular Weight | 384.898 |
| Exact Mass | 384.181580 |