GSK-3β inhibitor 14

Modify Date: 2025-08-25 13:38:16

Use of GSK-3β inhibitor 14

GSK-3β inhibitor 14 (Compound 6i), benzothiazepinone derivative, is a weak GSK-3β inhibitor (IC50 >100 μM)[1].

Name	WAY-333184
Synonym	More Synonyms

Description	GSK-3β inhibitor 14 (Compound 6i), benzothiazepinone derivative, is a weak GSK-3β inhibitor (IC50 >100 μM)[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> GSK-3 Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3
References	[1]. Zhang P, et al. Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Eur J Med Chem. 2013 Mar;61:95-103.

Molecular Formula	C₁₇H₁₇NOS
Molecular Weight	283.39

1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-

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