RuBi-4AP

Modify Date: 2024-01-06 07:50:09

RuBi-4AP Structure
RuBi-4AP structure
Common Name RuBi-4AP
CAS Number 851956-02-0 Molecular Weight 672.57
Density N/A Boiling Point N/A
Molecular Formula C30H28Cl2N8Ru Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RuBi-4AP


RuBi-4AP, a derivative of 4-aminopyridine (4AP; HY-B0604), is a caged Kv channel blocker. RuBi-4AP contains a photolabile protecting group, allowing its effect to be controlled precisely in both space and time with light. RuBi-4AP can be used for the research of neuronal excitability, synaptic transmission, and signal propagation[1][2].

 Names

Name L-Tryptophan
Synonym More Synonyms

 RuBi-4AP Biological Activity

Description RuBi-4AP, a derivative of 4-aminopyridine (4AP; HY-B0604), is a caged Kv channel blocker. RuBi-4AP contains a photolabile protecting group, allowing its effect to be controlled precisely in both space and time with light. RuBi-4AP can be used for the research of neuronal excitability, synaptic transmission, and signal propagation[1][2].
Related Catalog
References

[1]. Zayat L, et al. A new strategy for neurochemical photodelivery: metal-ligand heterolytic cleavage. J Am Chem Soc. 2003 Jan 29;125(4):882-3.  

[2]. Rowan MJ, et al. Distinct Kv channel subtypes contribute to differences in spike signaling properties in the axon initial segment and presynaptic boutons of cerebellar interneurons. J Neurosci. 2014 May 7;34(19):6611-23.  

 Chemical & Physical Properties

Molecular Formula C30H28Cl2N8Ru
Molecular Weight 672.57
Exact Mass 204.09000
PSA 79.11000
LogP 1.82260

 Synonyms

(S)-(-)-2-Amino-3-(3-indolyl)propionic Acid