2,5-Difluorobenzyl bromide structure
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Common Name | 2,5-Difluorobenzyl bromide | ||
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CAS Number | 85117-99-3 | Molecular Weight | 207.015 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | 187.9±25.0 °C at 760 mmHg | |
Molecular Formula | C7H5BrF2 | Melting Point | 8ºC | |
MSDS | Chinese USA | Flash Point | 15.6±0.0 °C | |
Symbol |
GHS02, GHS05 |
Signal Word | Danger |
Name | 2,5-Difluorobenzyl bromide |
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Synonym | More Synonyms |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 187.9±25.0 °C at 760 mmHg |
Melting Point | 8ºC |
Molecular Formula | C7H5BrF2 |
Molecular Weight | 207.015 |
Flash Point | 15.6±0.0 °C |
Exact Mass | 205.954269 |
LogP | 3.09 |
Vapour Pressure | 0.8±0.3 mmHg at 25°C |
Index of Refraction | 1.523 |
Storage condition | Flammables area |
Symbol |
GHS02, GHS05 |
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Signal Word | Danger |
Hazard Statements | H225-H314 |
Precautionary Statements | P210-P280-P305 + P351 + P338-P310 |
Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | F:Flammable;C:Corrosive; |
Risk Phrases | R11;R22;R34 |
Safety Phrases | S26-S36/37/39-S45-S16 |
RIDADR | UN 2924 3/PG 2 |
WGK Germany | 3 |
Packaging Group | III |
Hazard Class | 8 |
~% 2,5-Difluoroben... CAS#:85117-99-3 |
Literature: Journal of Medicinal Chemistry, , vol. 31, # 5 p. 1005 - 1009 |
Precursor 1 | |
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DownStream 10 | |
Aryl sulfones: a new class of gamma-secretase inhibitors.
Bioorg. Med. Chem. Lett. 15(10) , 2685-8, (2005) The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived gamma-secretase inhibitors for the potential treatment of Alzheimer's disease is described. |
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Synthesis and evaluation of [(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]cyclohexanes and 4-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]piperidines as DPP-4 inhibitors.
Bioorg. Med. Chem. Lett. 21 , 1880-1886, (2011) A series of 4-amino cyclohexanes and 4-substituted piperidines were prepared and evaluated for inhibition of DPP-4. Analog 20q displayed both good DPP-4 potency and selectivity against other proteases... |
2,5-Difluorobenzyl bromide |
α-Bromo-2,5-difluorotoluene |
2-(Bromomethyl)-1,4-difluorobenzene |
Benzene, 2-(bromomethyl)-1,4-difluoro- |
EINECS 285-651-0 |
FR DF B1E |
MFCD00009897 |