2,5-Difluorobenzyl bromide structure
|
Common Name | 2,5-Difluorobenzyl bromide | ||
|---|---|---|---|---|
| CAS Number | 85117-99-3 | Molecular Weight | 207.015 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 187.9±25.0 °C at 760 mmHg | |
| Molecular Formula | C7H5BrF2 | Melting Point | 8ºC | |
| MSDS | Chinese USA | Flash Point | 15.6±0.0 °C | |
| Symbol |
GHS02, GHS05 |
Signal Word | Danger | |
| Name | 2,5-Difluorobenzyl bromide |
|---|---|
| Synonym | More Synonyms |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 187.9±25.0 °C at 760 mmHg |
| Melting Point | 8ºC |
| Molecular Formula | C7H5BrF2 |
| Molecular Weight | 207.015 |
| Flash Point | 15.6±0.0 °C |
| Exact Mass | 205.954269 |
| LogP | 3.09 |
| Vapour Pressure | 0.8±0.3 mmHg at 25°C |
| Index of Refraction | 1.523 |
| Storage condition | Flammables area |
| Symbol |
GHS02, GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H314 |
| Precautionary Statements | P210-P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | F:Flammable;C:Corrosive; |
| Risk Phrases | R11;R22;R34 |
| Safety Phrases | S26-S36/37/39-S45-S16 |
| RIDADR | UN 2924 3/PG 2 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 8 |
|
~%
2,5-Difluoroben... CAS#:85117-99-3 |
| Literature: Journal of Medicinal Chemistry, , vol. 31, # 5 p. 1005 - 1009 |
| Precursor 1 | |
|---|---|
| DownStream 10 | |
|
Aryl sulfones: a new class of gamma-secretase inhibitors.
Bioorg. Med. Chem. Lett. 15(10) , 2685-8, (2005) The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived gamma-secretase inhibitors for the potential treatment of Alzheimer's disease is described. |
|
|
Synthesis and evaluation of [(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]cyclohexanes and 4-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]piperidines as DPP-4 inhibitors.
Bioorg. Med. Chem. Lett. 21 , 1880-1886, (2011) A series of 4-amino cyclohexanes and 4-substituted piperidines were prepared and evaluated for inhibition of DPP-4. Analog 20q displayed both good DPP-4 potency and selectivity against other proteases... |
| 2,5-Difluorobenzyl bromide |
| α-Bromo-2,5-difluorotoluene |
| 2-(Bromomethyl)-1,4-difluorobenzene |
| Benzene, 2-(bromomethyl)-1,4-difluoro- |
| EINECS 285-651-0 |
| FR DF B1E |
| MFCD00009897 |