<Suppliers Price>

2,5-Difluorobenzyl bromide

Names

[ CAS No. ]:
85117-99-3

[ Name ]:
2,5-Difluorobenzyl bromide

[Synonym ]:
2,5-Difluorobenzyl bromide
α-Bromo-2,5-difluorotoluene
2-(Bromomethyl)-1,4-difluorobenzene
Benzene, 2-(bromomethyl)-1,4-difluoro-
EINECS 285-651-0
FR DF B1E
MFCD00009897

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
187.9±25.0 °C at 760 mmHg

[ Melting Point ]:
8ºC

[ Molecular Formula ]:
C7H5BrF2

[ Molecular Weight ]:
207.015

[ Flash Point ]:
15.6±0.0 °C

[ Exact Mass ]:
205.954269

[ LogP ]:
3.09

[ Vapour Pressure ]:
0.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.523

[ Storage condition ]:
Flammables area

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H314

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;C:Corrosive;

[ Risk Phrases ]:
R11;R22;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S16

[ RIDADR ]:
UN 2924 3/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

Synthetic Route

Precursor & DownStream

Articles

Aryl sulfones: a new class of gamma-secretase inhibitors.

Bioorg. Med. Chem. Lett. 15(10) , 2685-8, (2005)

The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived gamma-secretase inhibitors for the potential treatment of Alzheimer's disease is described.

Synthesis and evaluation of [(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]cyclohexanes and 4-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]piperidines as DPP-4 inhibitors.

Bioorg. Med. Chem. Lett. 21 , 1880-1886, (2011)

A series of 4-amino cyclohexanes and 4-substituted piperidines were prepared and evaluated for inhibition of DPP-4. Analog 20q displayed both good DPP-4 potency and selectivity against other proteases...


More Articles


Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.