(3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-4H-1-benzopyran-4-one

Modify Date: 2024-02-27 16:34:13

(3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-4H-1-benzopyran-4-one structure	Common Name	(3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-4H-1-benzopyran-4-one
	CAS Number	849727-88-4	Molecular Weight	286.279
	Density	1.5±0.1 g/cm3	Boiling Point	574.8±39.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	220.0±20.6 °C

Use of (3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-4H-1-benzopyran-4-one

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells[1].

Name	(3R)-5,7-Dihydroxy-3-(4-hydroxybenzyl)-2,3-dihydro-4H-chromen-4-one
Synonym	More Synonyms

Description	(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
In Vitro	(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone has an GI50 value of 35.8 µM on proliferation of human retinal microvascular endothelial cells (HRECs)[1]. (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone (10 µM, 30 µM, and 100 µM; 8 hours) significantly decreases HRECs overall tubule formation and in a dose-dependent manner[1].
References	[1]. Sianne L Schwikkard, et al. Antiangiogenic Activity and Cytotoxicity of Triterpenoids and Homoisoflavonoids from Massonia pustulata and Massonia bifolia. Planta Med. 2018 Jul;84(9-10):638-644.

Density	1.5±0.1 g/cm3
Boiling Point	574.8±39.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₄O₅
Molecular Weight	286.279
Flash Point	220.0±20.6 °C
Exact Mass	286.084137
LogP	3.65
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.684
InChIKey	FIASLUPJXGTCKM-SNVBAGLBSA-N
SMILES	O=C1c2c(O)cc(O)cc2OCC1Cc1ccc(O)cc1

(3R)-5,7-Dihydroxy-3-(4-hydroxybenzyl)-2,3-dihydro-4H-chromen-4-one

4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-, (3R)-

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(3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-4H-1-benzopyran-4-one

Use of (3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-4H-1-benzopyran-4-one

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.