TPI 287
Modify Date: 2025-08-25 20:57:31
TPI 287 structure
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Common Name | TPI 287 | ||
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| CAS Number | 849213-15-6 | Molecular Weight | 869.990 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 857.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C46H63NO15 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 472.3±34.3 °C | |
Use of TPI 287TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain[1]. |
| Name | tpi287 |
|---|---|
| Synonym | More Synonyms |
| Description | TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain[1]. |
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| Related Catalog | |
| In Vivo | TPI-287 (i.v., 18 mg/kg, every 4 days, 41 days) 在接种了 231-BR 乳腺癌细胞的小鼠肿瘤模型中，可以有效减小肿瘤体积，抑制肿瘤的生长[1]。 |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 857.4±65.0 °C at 760 mmHg |
| Molecular Formula | C46H63NO15 |
| Molecular Weight | 869.990 |
| Flash Point | 472.3±34.3 °C |
| Exact Mass | 869.419800 |
| PSA | 211.68000 |
| LogP | 7.97 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.573 |
| Hexanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-5-methyl-, (1S,2S,4S,7S,7aR,10aS,11aR,13aS,13bR,13cS)-7,13a-bis(acetyloxy)-1-(benzoyloxy)-9-ethenyl-1,3,4,7,7a,10a,11,11a,13,13a,13b,13c-dodecahydro-2-hydroxy-5,13c,14,14-tetramethyl-2,6-methano-2H-cyclodec[de]oxeto[3,2-g][1,3]benzodioxin-4-yl ester, (2R,3S)- |
| TPI-287 |
| (1R,2S,5R,7S,11R,12S,15S,17S,18S,19S)-2,12-Diacetoxy-17-hydroxy-15-{[(2R,3S)-2-hydroxy-5-methyl-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)hexanoyl]oxy}-14,19,20,20-tetramethyl-9-vinyl-4,8,10-trioxa ;pentacyclo[9.7.1.1.0.0]icos-13-en-18-yl benzoate |