Fluorofenidone
Modify Date: 2025-08-25 06:31:16
Fluorofenidone structure
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Common Name | Fluorofenidone | ||
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| CAS Number | 848353-85-5 | Molecular Weight | 203.21200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H10FNO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FluorofenidoneFluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway[1][2]. |
| Name | 1-(3-fluorophenyl)-5-methylpyridin-2-one |
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| Synonym | More Synonyms |
| Description | Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway[1][2]. |
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| Related Catalog | |
| References |
| Molecular Formula | C12H10FNO |
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| Molecular Weight | 203.21200 |
| Exact Mass | 203.07500 |
| PSA | 22.00000 |
| LogP | 2.28500 |
| InChIKey | JDZYVVUJIQYGRX-UHFFFAOYSA-N |
| SMILES | Cc1ccc(=O)n(-c2cccc(F)c2)c1 |
| fluorofenidone |