NCGC 00067819

Modify Date: 2025-08-25 08:09:10

NCGC 00067819 Structure
NCGC 00067819 structure
Common Name NCGC 00067819
CAS Number 847163-23-9 Molecular Weight 346.406
Density 1.5±0.1 g/cm3 Boiling Point 550.0±50.0 °C at 760 mmHg
Molecular Formula C19H14N4OS Melting Point N/A
MSDS N/A Flash Point 286.4±30.1 °C

 Use of NCGC 00067819


NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay; potentiates cAMP production induced by NKH 477.

 Names

Name 4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidine
Synonym More Synonyms

 NCGC 00067819 Biological Activity

Description NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay; potentiates cAMP production induced by NKH 477.
References References 1. Xia M, et al. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2412-7. View Related Products by Target CREB/CBP

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 550.0±50.0 °C at 760 mmHg
Molecular Formula C19H14N4OS
Molecular Weight 346.406
Flash Point 286.4±30.1 °C
Exact Mass 346.088837
LogP 3.39
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.796
InChIKey FSHFRKKIBVABAJ-UHFFFAOYSA-N
SMILES Cc1nc(SCc2nc3ccccc3[nH]2)c2oc3ccccc3c2n1

 Synonyms

4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidine
4-[(1H-Benzimidazol-2-ylmethyl)sulfanyl]-2-methyl[1]benzofuro[3,2-d]pyrimidine
Benzofuro[3,2-d]pyrimidine, 4-[(1H-benzimidazol-2-ylmethyl)thio]-2-methyl-
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