847163-23-9
847163-23-9 structure
- Name: NCGC 00067819
- Chemical Name: 4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidine
- CAS Number: 847163-23-9
- Molecular Formula: C19H14N4OS
- Molecular Weight: 346.406
- Create Date: 2020-01-12 10:44:51
- Modify Date: 2025-08-25 08:09:10
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NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay; potentiates cAMP production induced by NKH 477.
| Name | 4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidine |
|---|---|
| Synonyms |
4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidine
4-[(1H-Benzimidazol-2-ylmethyl)sulfanyl]-2-methyl[1]benzofuro[3,2-d]pyrimidine Benzofuro[3,2-d]pyrimidine, 4-[(1H-benzimidazol-2-ylmethyl)thio]-2-methyl- |
| Description | NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay; potentiates cAMP production induced by NKH 477. |
|---|---|
| References | References 1. Xia M, et al. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2412-7. View Related Products by Target CREB/CBP |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 550.0±50.0 °C at 760 mmHg |
| Molecular Formula | C19H14N4OS |
| Molecular Weight | 346.406 |
| Flash Point | 286.4±30.1 °C |
| Exact Mass | 346.088837 |
| LogP | 3.39 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.796 |