CP94253 hydrochloride

Modify Date: 2024-01-17 19:21:37

CP94253 hydrochloride Structure
CP94253 hydrochloride structure
Common Name CP94253 hydrochloride
CAS Number 845861-39-4 Molecular Weight 293.79200
Density N/A Boiling Point N/A
Molecular Formula C15H20ClN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CP94253 hydrochloride


CP94253 hydrochloride is a potent and selective agonist of 5-HT1B receptor (Ki= 2 nM in a radioligand binding assay).Ki values for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors are 89, 49, 860, and 1600 nM respectively[1]. CP94253 hydrochloride is centrally active upon systemic administration in vivo[2].

 Names

Name 1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, hydrochloride ()
Synonym More Synonyms

 CP94253 hydrochloride Biological Activity

Description CP94253 hydrochloride is a potent and selective agonist of 5-HT1B receptor (Ki= 2 nM in a radioligand binding assay).Ki values for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors are 89, 49, 860, and 1600 nM respectively[1]. CP94253 hydrochloride is centrally active upon systemic administration in vivo[2].
Related Catalog
References

[1]. Koe et al (1992) Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253. Drug Dev.Res. 26 241

[2]. Knobelman DA, Kung HF, Lucki I. Regulation of extracellular concentrations of 5-hydroxytryptamine (5-HT) in mouse striatum by 5-HT(1A) and 5-HT(1B) receptors. J Pharmacol Exp Ther. 2000 Mar;292(3):1111-7

 Chemical & Physical Properties

Molecular Formula C15H20ClN3O
Molecular Weight 293.79200
Exact Mass 293.12900
PSA 49.94000
LogP 3.85920

 Synonyms

1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, monohydrochloride
ICI 154,129
CP 94253 hydrochloride
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here



Get all suppliers and price by the below link:

CP94253 hydrochloride suppliers

CP94253 hydrochloride price