gepirone

Modify Date: 2025-08-24 07:17:02

gepirone Structure
gepirone structure
 Common Name gepirone
CAS Number 83928-76-1 Molecular Weight 359.47
Density 1.1±0.1 g/cm3 Boiling Point 562.3±60.0 °C at 760 mmHg
Molecular Formula C19H29N5O2 Melting Point N/A
MSDS N/A Flash Point 293.8±32.9 °C

 Use of gepirone


Gepirone is a selectively and affinitive 5-HT1A agonist. Gepirone binds selectively to 5-HT1A receptor binding site. Gepirone acts as an antidepressant agent can be used for anxiety and major depressive disorder research[1].

 Names

Name 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione
Synonym More Synonyms

 gepirone Biological Activity

Description Gepirone is a selectively and affinitive 5-HT1A agonist. Gepirone binds selectively to 5-HT1A receptor binding site. Gepirone acts as an antidepressant agent can be used for anxiety and major depressive disorder research[1].
Related Catalog
Target

5-HT1A Receptor

References

[1]. Mendelson SD, et al. Effects of 5-HT1A selective anxiolytics on lordosis behavior: interactions with progesterone. Eur J Pharmacol. 1986 Dec 16;132(2-3):323-6.  

[2]. Blier P, et al. Modification of 5-HT neuron properties by sustained administration of the 5-HT1A agonist gepirone: electrophysiological studies in the rat brain. Synapse. 1987;1(5):470-80.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 562.3±60.0 °C at 760 mmHg
Molecular Formula C19H29N5O2
Molecular Weight 359.47
Flash Point 293.8±32.9 °C
Exact Mass 359.232117
PSA 69.64000
LogP 2.95
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.542

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3,3-Dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]glutarimide
gepirone
4,4-Dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione
4,4-Dimethyl-1-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}piperidine-2,6-dione
2,6-Piperidinedione, 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-
4,4-Dimethyl-1-{4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl}-2,6-piperidinedione
4,4-dimethyl-1-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]piperidine-2,6-dione
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Related Compounds: More...
Gepirone ER
83928-66-9
Gepirone-d8
2749331-28-8
5-OH gepirone
87789-60-4
3'-OH gepirone
345894-78-2
benzyl N-[(1s,3s)-3-hydroxy-1-phenylcyclobutyl]carbamate
2680786-49-4
Benzyl 3-(4-hydroxyphenyl)pyrrolidine-1-carboxylate
2680699-64-1
benzyl N-{[2-(hydroxymethyl)bicyclo[2.2.2]octan-2-yl]methyl}carbamate
2680748-27-8
Benzyl 2-(2-hydroxycyclopentyl)piperidine-1-carboxylate
2680712-98-3
2-(N-benzylacetamido)-3-cyclohexylpropanoic acid
2680611-94-1
Benzyl 8-(hydroxymethyl)-7-azaspiro[4.5]decane-7-carboxylate
2680679-08-5
rac-(1R,3R)-3-(1-ethyl-1H-pyrazol-4-yl)-2,2-dimethylcyclopropane-1-carboxylic acid
2227768-06-9
rac-benzyl (3R,4R)-3-cyclopentyl-4-hydroxypiperidine-1-carboxylate
2679940-59-9
Benzyl (cyclopropylmethyl)(4-hydroxycyclohexyl)carbamate
2680791-27-7
3-hydroxy-3-(1H-1,2,4-triazol-3-yl)propanenitrile
2229100-94-9
Chemsrc provides gepirone(CAS#:83928-76-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of gepirone are included as well.>> amp version: gepirone

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