Cetirizine Impurity C

Modify Date: 2025-09-27 13:41:50

Cetirizine Impurity C structure	Common Name	Cetirizine Impurity C
	CAS Number	83881-59-8	Molecular Weight	388.888
	Density	1.2±0.1 g/cm3	Boiling Point	536.2±45.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₅ClN₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	278.1±28.7 °C

Use of Cetirizine Impurity C

Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1][2].

Name	2-[2-[4-[(2-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid
Synonym	More Synonyms

Description	Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Endocrinology Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. [2]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.

Description

Related Catalog

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor

Research Areas >> Endocrinology

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

References

[1]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5.

[2]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.

Density	1.2±0.1 g/cm3
Boiling Point	536.2±45.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₅ClN₂O₃
Molecular Weight	388.888
Flash Point	278.1±28.7 °C
Exact Mass	388.155365
PSA	53.01000
LogP	2.16
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.589

2-Chlorocetirizine

Cetirizine 2-Chloro Impurity Dihydrochloride

Acetic acid, 2-[2-[4-[(2-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-

UNII-4DG59P89YF

Cetirizine impurity C

UNII:4DG59P89YF

(2-{4-[(2-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetic acid

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China
Product Name: Cetirizine Imp. C (EP);
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China
Product Name: Cetirizine Impurity C
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
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Email: sales@dcchemicals.com

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