Leucosceptoside A

Modify Date: 2024-01-11 08:14:36

Leucosceptoside A structure	Common Name	Leucosceptoside A
	CAS Number	83529-62-8	Molecular Weight	638.61400
	Density	1.545g/cm3	Boiling Point	884.547ºC at 760 mmHg
	Molecular Formula	C₃₀H₃₈O₁₅	Melting Point	N/A
	MSDS	N/A	Flash Point	283.993ºC

Use of Leucosceptoside A

Leucosceptoside A is a phenylethanoid glycoside with anti-hyperglycemic and anti-hypertensive activities. Leucosceptoside A shows inhibitory activity against α-glucosidase and PKCα (IC50 of 19.0 μM)[1][2][3].

Name	[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoate

Description	Leucosceptoside A is a phenylethanoid glycoside with anti-hyperglycemic and anti-hypertensive activities. Leucosceptoside A shows inhibitory activity against α-glucosidase and PKCα (IC50 of 19.0 μM)[1][2][3].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE) Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Signaling Pathways >> TGF-beta/Smad >> PKC
Target	PKCα:19 μM (IC50)
In Vitro	Leucosceptoside A shows weak angiotensin converting enzyme (ACE) inhibitory effect[1]. Leucosceptoside A (4-16 μM) significantly reduces 1-methyl-4-phenylpyridinium ion (MPP+)-induced death of mesencephalic neurons[2].
References	[1]. Chika Ifeanyi Chukwuma, et al. Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review. J Ethnopharmacol. 2019 May 10;235:329-360. [2]. Yan-Yun Li, et al. Pedicularioside A from Buddleia lindleyana inhibits cell death induced by 1-methyl-4-phenylpyridinium ions (MPP+) in primary cultures of rat mesencephalic neurons. Eur J Pharmacol. 2008 Jan 28;579(1-3):134-40. [3]. B N Zhou, et al. Phenylethanoid glycosides from Digitalis purpurea and Penstemon linarioides with PKCalpha-inhibitory activity. J Nat Prod. 1998 Nov;61(11):1410-2.

Density	1.545g/cm3
Boiling Point	884.547ºC at 760 mmHg
Molecular Formula	C₃₀H₃₈O₁₅
Molecular Weight	638.61400
Flash Point	283.993ºC
Exact Mass	638.22100
PSA	234.29000
Index of Refraction	1.664

BioBioPha
China
Product Name: Leucosceptoside A
Price: ￥3900.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

DC Chemicals Limited
China
Product Name: Leucosceptoside A
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: LEUCOSCEPTOSIDEA
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

Leucosceptoside A suppliers

Leucosceptoside A price

Leucosceptoside A

Use of Leucosceptoside A

Names

Leucosceptoside A Biological Activity

Chemical & Physical Properties