flurithromycin

Modify Date: 2024-01-03 18:37:47

flurithromycin structure	Common Name	flurithromycin
	CAS Number	82664-20-8	Molecular Weight	751.91700
	Density	1.22g/cm3	Boiling Point	814.6ºC at 760 mmHg
	Molecular Formula	C₃₇H₆₆FNO₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	446.5ºC

Use of flurithromycin

Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections[1][2][3].

Name	flurithromycin
Synonym	More Synonyms

Description	Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Flurithromycin (72 h) inhibits the growth of H. pylori strains with MIC50 and MIC90 values of 0.156 and 0.625 mg/L, respectively[1]. Flurithromycin displays antibacterial activity in clinical isolates of respiratory pathogens (MIC: 1.5-6 ng/mL for Streptococcus pneumonia, 12-400 ng/mL for Haemophilus influenza, 100 to 3100 ng/mL for Staphylococcus aureus)[3].

Density	1.22g/cm3
Boiling Point	814.6ºC at 760 mmHg
Molecular Formula	C₃₇H₆₆FNO₁₃
Molecular Weight	751.91700
Flash Point	446.5ºC
Exact Mass	751.45200
PSA	193.91000
LogP	1.87770
Index of Refraction	1.531

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KF4800000

CHEMICAL NAME :: Erythromycin, 8-fluoro-

CAS REGISTRY NUMBER :: 82664-20-8

LAST UPDATED :: 199310

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C37-H66-F-N-O13

MOLECULAR WEIGHT :: 752.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,214,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,214,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 37,84-108,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 790 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 37,84-108,1984

Hazard Codes	F
Risk Phrases	10
Safety Phrases	16

fluritromicina

Huritromicina(sp)

8-fluoro-erythromyci

cl-932

8-fluoroerythromycin

P-0501-A

C1-932

(8S)-8-fluoroerythromycin A

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: FLURITHROMYCIN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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flurithromycin

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