JNJ-20788560

Modify Date: 2024-02-01 11:21:47

JNJ-20788560 Structure
JNJ-20788560 structure
Common Name JNJ-20788560
CAS Number 825649-28-3 Molecular Weight 388.50200
Density N/A Boiling Point N/A
Molecular Formula C25H28N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JNJ-20788560


JNJ-20788560 is a selective and orally active delta opioid receptor agonist with an affinity of 2.0 nM for DOR (rat brain cortex binding assay). JNJ-20788560 also is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. JNJ-20788560 can be used for the research of the relief of inflammatory hyperalgesia[1].

 Names

Name 9-[(1R,5S)-8-azabicyclo[3.2.1]octan-3-ylidene]-N,N-diethylxanthene-3-carboxamide
Synonym More Synonyms

 JNJ-20788560 Biological Activity

Description JNJ-20788560 is a selective and orally active delta opioid receptor agonist with an affinity of 2.0 nM for DOR (rat brain cortex binding assay). JNJ-20788560 also is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. JNJ-20788560 can be used for the research of the relief of inflammatory hyperalgesia[1].
Related Catalog
References

[1]. Codd EE, et al. JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. J Pharmacol Exp Ther. 2009 Apr;329(1):241-51.  

 Chemical & Physical Properties

Molecular Formula C25H28N2O2
Molecular Weight 388.50200
Exact Mass 388.21500
PSA 41.57000
LogP 5.31940

 Synonyms

unii-99hyh9k6mz