Retosiban
Modify Date: 2025-08-27 17:41:43
Retosiban structure
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Common Name | Retosiban | ||
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| CAS Number | 820957-38-8 | Molecular Weight | 494.58300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H34N4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RetosibanRetosiban (GSK221149A) is a potent and selective oxytocin antagonist with a Ki of 0.65 nM. |
| Name | (3R,6R)-6-[(2S)-butan-2-yl]-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2-methyl-1,3-oxazol-4-yl)-2-morpholin-4-yl-2-oxoethyl]piperazine-2,5-dione |
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| Synonym | More Synonyms |
| Description | Retosiban (GSK221149A) is a potent and selective oxytocin antagonist with a Ki of 0.65 nM. |
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| Related Catalog | |
| Target |
IC50: 0.65 nM (Oxytocin)[1] |
| References |
| Molecular Formula | C27H34N4O5 |
|---|---|
| Molecular Weight | 494.58300 |
| Exact Mass | 494.25300 |
| PSA | 108.47000 |
| LogP | 2.19130 |
| Storage condition | 2-8°C |
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~%
Retosiban CAS#:820957-38-8 |
| Literature: GLAXO GROUP LIMITED Patent: WO2005/840 A1, 2005 ; Location in patent: Page/Page column 12-13 ; WO 2005/000840 A1 |
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Detail
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| Literature: GLAXO GROUP LIMITED Patent: WO2005/840 A1, 2005 ; Location in patent: Page/Page column 13-15 ; WO 2005/000840 A1 |
![{(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-6-[(1S)-1-methylpropyl]-2,5-dioxo-1-piperazinyl}(2-methyl-1,3-oxazol-4-yl)acetic acid structure](https://image.chemsrc.com/caspic/131/820957-45-7.png)
| UNII-GIE06H28OX |
| Retosiban |