Sodium ionophore III

Modify Date: 2024-01-09 09:08:01

Sodium ionophore III structure	Common Name	Sodium ionophore III
	CAS Number	81686-22-8	Molecular Weight	552.78800
	Density	1.12g/cm3	Boiling Point	709.4ºC at 760 mmHg
	Molecular Formula	C₃₄H₅₂N₂O₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	382.8ºC
	Symbol	GHS07	Signal Word	Warning

Use of Sodium ionophore III

Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc.

Name	N,N-dicyclohexyl-2-[2-[2-(dicyclohexylamino)-2-oxoethoxy]phenoxy]acetamide
Synonym	More Synonyms

Description	Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Cardiovascular Disease
In Vitro	Preincubation of the cells with the Na+ ionophore sodium ionophore III not only stimulated caffeate reduction, but completely abolished ATP synthesis. Addition of sodium ionophore III to cells in the steady state of caffeate reduction immediately dissipated the intracellular ATP level[1]. Lactate-sulfate grown cells are insensitive to the Na+ ionophore, ETH2120[2]. Sodium ionophore III ligand is a very effective receptor for the Eu3+ and Am3+ cations and can be considered as a potential extraction agent for nuclear iste treatment[3].
References	[1]. Imkamp F, et al. Chemiosmotic energy conservation with Na(+) as the coupling ion during hydrogen-dependent caffeate reduction by Acetobacterium woodii. J Bacteriol. 2002 Apr;184(7):1947-51. [2]. Wang L, et al. The role of Rnf in ion gradient formation in Desulfovibrio alaskensis. PeerJ. 2016 Apr 14;4:e1919. [3]. Makrlík, E, et al. Sodium Ionophore III as Very Effective Receptor for Trivalent Europium and Americium.J Solution Chem (2016) 45: 463.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H335
Precautionary Statements	P261
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	37
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

T. Maruizumi et al.

Mikrochim. Acta I , 331, (1986)

N,N,N',N'-Tetracyclohexyl-1,2-phenylenedioxydiacetamide

N,N-Dicyclohexyl-2-(2-[2-(dicyclohexylamino)-2-oxoethoxy]phenoxy)acetamide

ETH 2120

MFCD00077941

Sodium ionophore III

Acetamide,2,2'-[1,2-phenylenebis(oxy)]bis[N,N-dicyclohexyl

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Price: $119/10mM*1mLinDMSO

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