(5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid

Modify Date: 2024-01-10 19:13:07

(5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid Structure
(5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid structure
Common Name (5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid
CAS Number 808769-54-2 Molecular Weight 472.700
Density 1.1±0.1 g/cm3 Boiling Point 584.1±50.0 °C at 760 mmHg
Molecular Formula C30H48O4 Melting Point N/A
MSDS N/A Flash Point 321.1±26.6 °C

 Use of (5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid


3α,22β-Dihydroxyolean-12-en-29-oic acid is a terpenoid isolated from Maytenus royleanus cufodontis. 3α,22β-Dihydroxyolean-12-en-29-oic acid shows antiproliferative activity for HeLa, PC-3 and HCCLM3 cell lines with an IC50 values of 32.64 µM, 9.09 µM and 6.9 µM, respectively[1][2][3].

 Names

Name 3,22-Dihydroxyolean-12-en-29-oic acid
Synonym More Synonyms

  Biological Activity

Description 3α,22β-Dihydroxyolean-12-en-29-oic acid is a terpenoid isolated from Maytenus royleanus cufodontis. 3α,22β-Dihydroxyolean-12-en-29-oic acid shows antiproliferative activity for HeLa, PC-3 and HCCLM3 cell lines with an IC50 values of 32.64 µM, 9.09 µM and 6.9 µM, respectively[1][2][3].
Related Catalog
References

[1]. Din A U, et al. Ficusonic acid: a new cytotoxic triterpene isolated from Maytenus royleanus (Wall. ex MA Lawson) cufodontis[J]. Journal of the Brazilian Chemical Society, 2013, 24: 663-668.

[2]. Ying YM, et al. Lupane- and Friedelane-Type Triterpenoids from Celastrus stylosus. Chem Biodivers. 2015 Aug;12(8):1222-8.  

[3]. Li C, et al. A new norditerpenoid from Euonymus grandiflorus Wall. Nat Prod Res. 2013;27(19):1716-21.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 584.1±50.0 °C at 760 mmHg
Molecular Formula C30H48O4
Molecular Weight 472.700
Flash Point 321.1±26.6 °C
Exact Mass 472.355255
PSA 77.76000
LogP 7.32
Vapour Pressure 0.0±3.7 mmHg at 25°C
Index of Refraction 1.568

 Safety Information

Hazard Codes Xi

 Synonyms

(5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid
Olean-12-en-29-oic acid, 3,22-dihydroxy-, (5ξ,18α)-
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