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(5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid

Names

[ CAS No. ]:
808769-54-2

[ Name ]:
(5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid

[Synonym ]:
(5ξ,18α)-3,22-Dihydroxyolean-12-en-29-oic acid
Olean-12-en-29-oic acid, 3,22-dihydroxy-, (5ξ,18α)-

Biological Activity

[Description]:

3α,22β-Dihydroxyolean-12-en-29-oic acid is a terpenoid isolated from Maytenus royleanus cufodontis. 3α,22β-Dihydroxyolean-12-en-29-oic acid shows antiproliferative activity for HeLa, PC-3 and HCCLM3 cell lines with an IC50 values of 32.64 µM, 9.09 µM and 6.9 µM, respectively[1][2][3].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Din A U, et al. Ficusonic acid: a new cytotoxic triterpene isolated from Maytenus royleanus (Wall. ex MA Lawson) cufodontis[J]. Journal of the Brazilian Chemical Society, 2013, 24: 663-668.

[2]. Ying YM, et al. Lupane- and Friedelane-Type Triterpenoids from Celastrus stylosus. Chem Biodivers. 2015 Aug;12(8):1222-8.  

[3]. Li C, et al. A new norditerpenoid from Euonymus grandiflorus Wall. Nat Prod Res. 2013;27(19):1716-21.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
584.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H48O4

[ Molecular Weight ]:
472.700

[ Flash Point ]:
321.1±26.6 °C

[ Exact Mass ]:
472.355255

[ PSA ]:
77.76000

[ LogP ]:
7.32

[ Vapour Pressure ]:
0.0±3.7 mmHg at 25°C

[ Index of Refraction ]:
1.568

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds