MEGESTROL ACETATE + ETHINYLO-ESTRADIOL

Modify Date: 2025-09-22 16:23:48

MEGESTROL ACETATE + ETHINYLO-ESTRADIOL structure	Common Name	MEGESTROL ACETATE + ETHINYLO-ESTRADIOL
	CAS Number	8064-66-2	Molecular Weight	680.91200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₄H₅₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Name	Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-, acetate mixed with 19-nor-17.α.-pregna-1 ,3,5(10)-trien-2-yne-3,17-diol
Synonym	More Synonyms

Molecular Formula	C₄₄H₅₆O₆
Molecular Weight	680.91200
Exact Mass	680.40800
PSA	100.90000
LogP	8.18790

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU4140000

CHEMICAL NAME :: Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-, acetate mixed with 19-nor-17-alpha- pregna-1,3,5(10)-trien-2-yne-3,17-diol

CAS REGISTRY NUMBER :: 8064-66-2

LAST UPDATED :: 198910

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C24-H32-O4.C20-H24-O2

MOLECULAR WEIGHT :: 681.00

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 10584 ug/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - normocytic anemia

REFERENCE :: LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 1,273,1980

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 41 mg/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

REFERENCE :: BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 4,496,1975 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2430 ug/kg

SEX/DURATION :: female 30 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 1,1318,1963

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Product Name: MEGESTROL ACETATE + ETHINYLO-ESTRADIOL
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