18797-80-3

18797-80-3 structure

Name: Acetylcorynoline
Chemical Name: Acetylcorynoline
CAS Number: 18797-80-3
Molecular Formula: C₂₃H₂₃NO₆
Molecular Weight: 409.432
Catalog: Biochemical Plant extracts
Create Date: 2018-03-22 08:00:00
Modify Date: 2024-01-02 22:15:31
Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana, and has anti-inflammatory properties[1].

Name	Acetylcorynoline
Synonyms	(5bR)-6t-acetoxy-5b,13-dimethyl-(5br,12bc)-5b,6,7,12b,13,14-hexahydro-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol, 5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, acetate (ester), (5bR,6S,12bR)- corynoline acetate (+)-O-acetyl-corynoline N1513 Acetylcorynoline (+)-Corynolin-acetat O-Acetyl-13-methylchelidonine O-acetyl-13-methyl-chelidonine (+)-Corynolin-O-acetat

Description	Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana, and has anti-inflammatory properties[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Acetylcorynoline significantly inhibits the secretion of tumor necrosis factor-α, interleukin-6, and interleukin-12p70 by LPS-stimulated Dendritic cells (DCs)[1]. Acetylcorynoline significantly inhibits LPS-induced activation of IκB kinase and mitogen-activated protein kinase[1].
References	[1]. Fu RH, et al. Acetylcorynoline attenuates dopaminergic neuron degeneration and α-synuclein aggregation in animal models of Parkinson's disease. Neuropharmacology. 2014 Jul;82:108-20.