Calcium Levofolinate

Modify Date: 2024-01-02 16:06:17

Calcium Levofolinate Structure
Calcium Levofolinate structure
Common Name Calcium Levofolinate
CAS Number 80433-71-2 Molecular Weight 511.501
Density N/A Boiling Point N/A
Molecular Formula C20H21CaN7O7 Melting Point 240-250ºC
MSDS N/A Flash Point N/A

 Use of Calcium Levofolinate


Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.IC50 value: Target: Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used in combination chemotherapy with fluorouracil (5-FU) to treat colorectal cancer that has spread to other parts of the body. This medicine only treats the symptoms of colorectal cancer and does not treat the cancer itself.

 Names

Name calcium,(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
Synonym More Synonyms

 Calcium Levofolinate Biological Activity

Description Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.IC50 value: Target: Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used in combination chemotherapy with fluorouracil (5-FU) to treat colorectal cancer that has spread to other parts of the body. This medicine only treats the symptoms of colorectal cancer and does not treat the cancer itself.
Related Catalog
References

[1]. Levomefolic acid. From Wikipedia, the free encyclopedia

 Chemical & Physical Properties

Melting Point 240-250ºC
Molecular Formula C20H21CaN7O7
Molecular Weight 511.501
Exact Mass 511.112823
PSA 225.50000
Storage condition -20°C

 Synonyms

folinic acid calcium salt
Levoleucovorin calcium (USAN)
Calcium (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioate
calcium levofolinate
Fusilev (TN)
Calcium N-(p-((((6S)-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamate (1:1)
Isovorin
778XL6VBS8
Calcium 2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate
Levofolinate calcium (JAN)
Elvorine
Levoleucovorin (Calcium)
Calcium (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate
LEVOLEUCOVORIN CALCIUM
N-[4-[[[(6S)-2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic Acid Calcium Salt (1:1)
L-Glutamic acid, N-[4-[[[(6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1)
UNII-778XL6VBS8
Isovorin (TN)
Calcium levofolinate (INN)
MFCD00865527
Levofolinate
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