2'-Deoxy-2'-fluoro-D-inosine

Modify Date: 2024-01-03 19:16:58

2'-Deoxy-2'-fluoro-D-inosine Structure
2'-Deoxy-2'-fluoro-D-inosine structure
Common Name 2'-Deoxy-2'-fluoro-D-inosine
CAS Number 80049-87-2 Molecular Weight 270.22
Density 2.01g/cm3 Boiling Point 682.1ºC at 760mmHg
Molecular Formula C10H11FN4O4 Melting Point N/A
MSDS N/A Flash Point 366.3ºC

 Use of 2'-Deoxy-2'-fluoro-D-inosine


2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 9-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Synonym More Synonyms

 2'-Deoxy-2'-fluoro-D-inosine Biological Activity

Description 2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.01g/cm3
Boiling Point 682.1ºC at 760mmHg
Molecular Formula C10H11FN4O4
Molecular Weight 270.22
Flash Point 366.3ºC
Exact Mass 270.07600
PSA 113.26000
Index of Refraction 1.809

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2'-Deoxy-2'-fluoroinosine
2'-FLUORO-2'-DEOXYINOSINE
Inosine,2'-deoxy-2'-fluoro
2'-Dfin
2'-Deoxy-2'-fluoro-D-inosine
2'-F-2'-dI