55612-21-0

55612-21-0 structure

Name: 2'-Deoxy-2'-fluoro-5-iodouridine
Chemical Name: 1-[(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
CAS Number: 55612-21-0
Molecular Formula: C₉H₁₀FIN₂O₅
Molecular Weight: 372.09
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-01-10 04:54:14
Modify Date: 2024-01-31 10:30:40
2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
Synonyms	5-Iodo-1-(2-fluoro-2-deoxy-β-D-ribofuranosyl)uracil Uridine, 2'-deoxy-2'-fluoro-5-iodo- Uridine,2'-deoxy-2'-fluoro-5-iodo 2'-Deoxy-2'-fluoro-5-iodouridine 5-Ifdu 2`-epi-Fialuridine

Description	2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.