Vebufloxacin

Modify Date: 2025-08-26 17:24:10

Use of Vebufloxacin

DM8966 exhibits potent antibacterial activity against gram-positive and -negative bacteria.

Name	Vebufloxacin
Synonym	More Synonyms

Description	DM8966 exhibits potent antibacterial activity against gram-positive and -negative bacteria.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
Target	Bacteria[1]
In Vitro	A series of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids is synthesized and tested for antibacterial activities. Among them, DM8966 (OPC-7241) exhibits potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa, and OPC-7251 shows potent activity characteristically against Propionibacterium acnes[1].
References	[1]. Ishikawa H, et al. Studies on antibacterial agents. I. Synthesis of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids. Chem Pharm Bull (Tokyo). 1989 Aug;37(8):2103-8.

Density	1.41g/cm3
Boiling Point	579.1ºC at 760 mmHg
Molecular Formula	C₁₉H₂₂FN₃O₃
Molecular Weight	359.39500
Flash Point	304ºC
Exact Mass	359.16500
PSA	65.78000
LogP	2.10070
Index of Refraction	1.661
InChIKey	JATLJHBAMQKRDH-UHFFFAOYSA-N
SMILES	CC1CCc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23

Benofloxacin

8-(4-methyl-1-piperazinyl)-9-fluoro-5-methyl-6,7-dihydro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid

UNII-SXI3MP1G46

1h,5h-benzo[ij]quinolizine-2-carboxylic acid,9-fluoro-6,7-dihydro-5-methyl-8-(4-methyl-1-piperazinyl)-1-oxo

9-Fluoro-5-methyl-8-(4-methyl-1-piperazinyl)-6,7-dihydro-1-oxo-1H,5H-benzo<ij>quinolizine-2-carboxylic acid

DM8966

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Price: $696/1mg

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