Echinosporin

Modify Date: 2024-01-01 21:44:30

Echinosporin structure	Common Name	Echinosporin
	CAS Number	79127-35-8	Molecular Weight	223.18200
	Density	1.709g/cm3	Boiling Point	635.1ºC at 760 mmHg
	Molecular Formula	C₁₀H₉NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	337.9ºC

Use of Echinosporin

Echinosporin (XK-213) is an antibiotic. Echinosporin can be isolated from Amycolatopsis strain. Echinosporin has antifungal activity and antitumor activity[1][2].

Name	1,5-(epoxymethano)cyclopenta[c]pyran-3-carboxamide, 1,4a,5,7a-tetrahydro-5-hydroxy-8-oxo-, (1.α.,4a.β.,5.β.,7a.β.)-, (-)
Synonym	More Synonyms

Description	Echinosporin (XK-213) is an antibiotic. Echinosporin can be isolated from Amycolatopsis strain. Echinosporin has antifungal activity and antitumor activity[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Inflammation/Immunology
Target	MIC50: 64 μg/mL (Fusarium oxysporum); 64 μg/mL (Fusarium solani); 32 μg/mL (Alternaria panax); 64 μg/mL (Phoma herbarum)[2].
In Vitro	Echinosporin (XK-213) 对革兰氏阳性和阴性微生物表现出较弱的抗菌活性，并具有抗肿瘤活性[1]。 Echinosporin 对三七根腐病病原体具有抗真菌活性，包括 Fusarium oxysporum、Fusarium solani、Alternaria panax 和 Phoma herbarum，MIC50 值分别为 64、64、32 和 64 μg/mL[2]。
References	[1]. T Sato, et al. A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterization. J Antibiot (Tokyo). 1982 Mar;35(3):266-71. [2]. Xindong Xu, et al. Echinosporin antibiotics isolated from Amycolatopsis strain and their antifungal activity against root-rot pathogens of the Panax notoginseng. Folia Microbiol (Praha). 2019 Mar;64(2):171-175.

Density	1.709g/cm3
Boiling Point	635.1ºC at 760 mmHg
Molecular Formula	C₁₀H₉NO₅
Molecular Weight	223.18200
Flash Point	337.9ºC
Exact Mass	223.04800
PSA	98.85000
Index of Refraction	1.687

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JW5313000

CHEMICAL NAME :: Echinosporin

CAS REGISTRY NUMBER :: 79127-35-8

LAST UPDATED :: 198509

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H9-N-O5

MOLECULAR WEIGHT :: 223.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 54 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 35,266,1982

echinosporine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Echinosporin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,5-(Epoxymethano)cyclopenta[c]pyran-3-carboxamide,1,4a,5,7a-tetrahydro-5-hydroxy-8-oxo-, (1S,4aS,5S,7aS)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Echinosporin

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