excisanin A

Modify Date: 2024-01-18 12:14:12

excisanin A Structure
excisanin A structure
Common Name excisanin A
CAS Number 78536-37-5 Molecular Weight 350.45
Density 1.3±0.1 g/cm3 Boiling Point 558.7±50.0 °C at 760 mmHg
Molecular Formula C20H30O5 Melting Point N/A
MSDS N/A Flash Point 305.8±26.6 °C

 Use of excisanin A


Excisanin A is a potent anticancer agent. Excisanin A inhibits cell proliferation, migration, adhesion and invasion. Excisanin A decreases the expression of MMP-2, MMP-9, p-FAK, p-Src, integrin β1 protein. Excisanin A has the potential for the research of breast cancer[1].

 Names

Name (1S,4aR,6R,6aR,9R,10S,11aS,11bR,12R)-1,6,10,12-tetrahydroxy-4,4,11b-trimethyl-8-methylenedodecahydro-6a,9-methanocyclohepta[a]naphthalen-7(1H)-one
Synonym More Synonyms

 excisanin A Biological Activity

Description Excisanin A is a potent anticancer agent. Excisanin A inhibits cell proliferation, migration, adhesion and invasion. Excisanin A decreases the expression of MMP-2, MMP-9, p-FAK, p-Src, integrin β1 protein. Excisanin A has the potential for the research of breast cancer[1].
Related Catalog
References

[1]. Qin J, et al. A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling. Life Sci. 2013 Nov 4;93(18-19):655-63.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 558.7±50.0 °C at 760 mmHg
Molecular Formula C20H30O5
Molecular Weight 350.45
Flash Point 305.8±26.6 °C
Exact Mass 350.209320
PSA 97.99000
LogP 0.13
Vapour Pressure 0.0±3.4 mmHg at 25°C
Index of Refraction 1.600

 Safety Information

Hazard Codes Xi

 Synonyms

(1α,5β,7α,8α,9β,10α,12α,13α,14R)-1,7,12,14-Tetrahydroxykaur-16-en-15-one