l-valine-2-d1

Modify Date: 2024-01-21 16:51:31

l-valine-2-d1 Structure
l-valine-2-d1 structure
 Common Name l-valine-2-d1
CAS Number 77257-03-5 Molecular Weight 118.15300
Density N/A Boiling Point N/A
Molecular Formula C5H10DNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of l-valine-2-d1


L-Valine-d1 is the deuterium labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].

 Names

Name l-valine-2-d1
Synonym More Synonyms

 l-valine-2-d1 Biological Activity

Description L-Valine-d1 is the deuterium labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[3]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[4]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[5]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[6]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[7]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[8]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[9]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

 Chemical & Physical Properties

Molecular Formula C5H10DNO2
Molecular Weight 118.15300
Exact Mass 118.08500
PSA 63.32000
LogP 0.75460

 Synthetic Route

L-Valine structure

L-Valine

CAS#:72-18-4

~57%

l-valine-2-d1 Structure

l-valine-2-d1

CAS#:77257-03-5
Literature: Faleev, N. G.; Ruvinov, S. B.; Saporovskaya, M. B.; Belikov, V. M.; Zakomyrdina, L. N.; et al. Tetrahedron Letters, 1990 , vol. 31, # 48 p. 7051 - 7054
Sodium 3-methyl-2-oxobutanoate structure

Sodium 3-methyl...

CAS#:3715-29-5

~%

D-[2-2H]valine structure

D-[2-2H]valine

CAS#:77257-02-4
l-valine-2-d1 Structure

l-valine-2-d1

CAS#:77257-03-5
Literature: Tachibana, Yoji; Ando, Makoto; Kuzuhara, Hiroyoshi Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 12 p. 3652 - 3656
N/A structure

N/A

CAS#:1255087-80-9

~%

l-valine-2-d1 Structure

l-valine-2-d1

CAS#:77257-03-5
Literature: Oh, Joong-Suk; Kim, Kyung Il; Song, Choong Eui Organic and Biomolecular Chemistry, 2011 , vol. 9, # 23 p. 7983 - 7985
Ac-DL-[2-2H]Val structure

Ac-DL-[2-2H]Val

CAS#:62076-86-2

~%

l-valine-2-d1 Structure

l-valine-2-d1

CAS#:77257-03-5

N-acetyl-D-[2-2H]valine structure

N-acetyl-D-[2-2...

CAS#:101067-12-3
Literature: Baldwin; Adlington; Ting; et al. Tetrahedron, 1985 , vol. 41, # 16 p. 3339 - 3343
L-Valine structure

L-Valine

CAS#:72-18-4

~%

D-[2-2H]valine structure

D-[2-2H]valine

CAS#:77257-02-4
l-valine-2-d1 Structure

l-valine-2-d1

CAS#:77257-03-5
Literature: Faleev, N. G.; Ruvinov, S. B.; Saporovskaya, M. B.; Belikov, V. M.; Zakomyrdina, L. N.; et al. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989 , vol. 38, # 10 p. 2154 - 2156 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989 , # 10 p. 2341 - 2343

 Synonyms

L-[2',3',5',6'-2H4]tyrosine
L-tyrosine-d4
[2,3,5,6-2H]-L-tyrosine
L-Tyrosine-d4 (phenyl-d4)
L-4-Hydroxyphenyl-2,3,5,6-d4-alanine
<2',3',5',6'-2H4>-L-tyrosine
[2H4]-L-Tyrosine
L-[(2)H4]tyrosine
L-Tyrosine-(phenyl-d4)
L-[2-2H]valine
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