Chlorphenoxamine

Modify Date: 2025-08-26 12:23:44

Chlorphenoxamine Structure
Chlorphenoxamine structure
Common Name Chlorphenoxamine
CAS Number 77-38-3 Molecular Weight 303.82600
Density 1.093g/cm3 Boiling Point 383.7ºC at 760 mmHg
Molecular Formula C18H22ClNO Melting Point N/A
MSDS N/A Flash Point 185.9ºC

 Use of Chlorphenoxamine


Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. Target: Histamine Receptor

 Names

Name 2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine
Synonym More Synonyms

 Chlorphenoxamine Biological Activity

Description Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. Target: Histamine Receptor
Related Catalog

 Chemical & Physical Properties

Density 1.093g/cm3
Boiling Point 383.7ºC at 760 mmHg
Molecular Formula C18H22ClNO
Molecular Weight 303.82600
Flash Point 185.9ºC
Exact Mass 303.13900
PSA 12.47000
LogP 4.18170
Index of Refraction 1.551
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KR3185000
CHEMICAL NAME :
Ethylamine, 2-(1-(p-chlorophenyl)-1-phenylethoxy)-N,N-dimethyl-
CAS REGISTRY NUMBER :
77-38-3
BEILSTEIN REFERENCE NO. :
2057618
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H22-Cl-N-O
MOLECULAR WEIGHT :
303.86
WISWESSER LINE NOTATION :
GR DX1&R&O2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
376 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,237,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
167 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,237,1957

 Safety Information

Hazard Codes Xi
HS Code 2922199090

 Synthetic Route

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Chlorphenoxamine Structure

Chlorphenoxamine

CAS#:77-38-3

Literature: Tetrahedron Letters, , vol. 29, # 30 p. 3659 - 3662

~%

Chlorphenoxamine Structure

Chlorphenoxamine

CAS#:77-38-3

Literature: Tetrahedron Letters, , vol. 29, # 30 p. 3659 - 3662

~%

Chlorphenoxamine Structure

Chlorphenoxamine

CAS#:77-38-3

Literature: Tetrahedron Letters, , vol. 29, # 30 p. 3659 - 3662

~%

Chlorphenoxamine Structure

Chlorphenoxamine

CAS#:77-38-3

Literature: Tetrahedron Letters, , vol. 29, # 30 p. 3659 - 3662

~%

Chlorphenoxamine Structure

Chlorphenoxamine

CAS#:77-38-3

Literature: DE952715 , ; Collection of Czechoslovak Chemical Communications, , vol. 24, p. 3966,3974

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Clorfenossamina [DCIT]
2-(1-(4-Chlorophenyl)-1-phenylethoxy)-N,N-dimethylethanamine
Chlorphenoxamine [INN:BAN]
Clorfenoxamina [INN-Spanish]
{2-[1-(4-Chlor-phenyl)-1-phenyl-aethoxy]-aethyl}-dimethyl-amin
{2-[1-(4-chloro-phenyl)-1-phenyl-ethoxy]-ethyl}-dimethyl-amine
Chlorphenoxaminum [INN-Latin]
Contristamine
Chlorphenoxamine
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