4-Bromo-antibiotic
4-Bromo-antibiotic structure
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Common Name | 4-Bromo-antibiotic | ||
|---|---|---|---|---|
| CAS Number | 76455-48-6 | Molecular Weight | 602.51700 | |
| Density | 1.43g/cm3 | Boiling Point | 735.4ºC at 760 mmHg | |
| Molecular Formula | C29H36BrN3O6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 398.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 4-Bromo-antibiotic4-Bromo A23187 is a halogenated analog of the highly selective calcium ionophore A-23187. 4-Bromo A23187，a calcium modulator, induces apoptosis in different cells, including HL-60 cells[1]. |
| Name | 4-bromo-a23187 |
|---|
| Description | 4-Bromo A23187 is a halogenated analog of the highly selective calcium ionophore A-23187. 4-Bromo A23187，a calcium modulator, induces apoptosis in different cells, including HL-60 cells[1]. |
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| Related Catalog | |
| References |
| Density | 1.43g/cm3 |
|---|---|
| Boiling Point | 735.4ºC at 760 mmHg |
| Molecular Formula | C29H36BrN3O6 |
| Molecular Weight | 602.51700 |
| Flash Point | 398.5ºC |
| Exact Mass | 601.17900 |
| PSA | 126.68000 |
| LogP | 6.36530 |
| Index of Refraction | 1.628 |
| InChIKey | LDXQFZZGVTWFCF-FHYGWRBKSA-N |
| SMILES | CNc1c(Br)cc2oc(CC3OC4(CCC3C)OC(C(C)C(=O)c3ccc[nH]3)C(C)CC4C)nc2c1C(=O)O |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H315-H319-H332-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
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Mast cell histamine-induced calcium transients in cultured human peritoneal mesothelial cells.
Perit. Dial. Int. 18(6) , 626-36, (1998) Peritoneal inflammation results from a complex interplay of events initiated by macrophage activity in response to infection, with the stimulation of mesothelial cell cytokine release amplifying the r... |
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Activity-dependent development of calcium regulation in growing motor axons.
J. Neurosci. 18(13) , 4966-72, (1998) In cultured nerve cord explants from the crayfish (Procambarus clarkii), the normal impulse activity levels of growing motor axons determine their response to Ca2+ influx. During depolarization or Ca2... |
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Intestinal anion exchanger down-regulated in adenoma (DRA) is inhibited by intracellular calcium.
J. Biol. Chem. 284(29) , 19744-53, (2009) The Na/H exchanger 3 (NHE3) and the Cl/HCO(3) exchanger down-regulated in adenoma (DRA) together facilitate intestinal electroneutral NaCl absorption. Elevated Ca(2+)(i) inhibits NHE3 through mechanis... |