Phthalic Acid Anhydride-d4

Modify Date: 2024-01-02 16:05:18

Phthalic Acid Anhydride-d4 Structure
Phthalic Acid Anhydride-d4 structure
Common Name Phthalic Acid Anhydride-d4
CAS Number 75935-32-9 Molecular Weight 152.14000
Density 1.483g/cm3 Boiling Point 284ºC(lit.)
Molecular Formula C8D4O3 Melting Point 131-134ºC(lit.)
MSDS Chinese USA Flash Point 139.7ºC
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Use of Phthalic Acid Anhydride-d4


Phthalic Acid Anhydride-d4 is the deuterium labeled Phthalic Acid Anhydride-d4[1].

 Names

Name 4,5,6,7-tetradeuterio-2-benzofuran-1,3-dione
Synonym More Synonyms

 Phthalic Acid Anhydride-d4 Biological Activity

Description Phthalic Acid Anhydride-d4 is the deuterium labeled Phthalic Acid Anhydride-d4[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Density 1.483g/cm3
Boiling Point 284ºC(lit.)
Melting Point 131-134ºC(lit.)
Molecular Formula C8D4O3
Molecular Weight 152.14000
Flash Point 139.7ºC
Exact Mass 152.04100
PSA 43.37000
LogP 0.99720
Index of Refraction 1.612
Storage condition 2-8°C

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H315-H317-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases 26-36
RIDADR UN 2214 8/PG 3

 Synthetic Route

~99%

Phthalic Acid Anhydride-d4 Structure

Phthalic Acid A...

CAS#:75935-32-9

Literature: Verbeeck, Stefan; Herrebout, Wouter A.; Gulevskaya, Anna V.; Van Der Veken, Benjamin J.; Maes, Bert U. W. Journal of Organic Chemistry, 2010 , vol. 75, # 15 p. 5126 - 5133

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

Tetradeuterio-phthalsaeureanhydrid
Phthalic anhydride-d4
d4-phthalic anhydride
phthalic acid anhydride-d4
MFCD00145119