Z-Leu-Leu-Glu-βNA

Modify Date: 2025-08-24 23:23:27

Z-Leu-Leu-Glu-βNA structure	Common Name	Z-Leu-Leu-Glu-βNA
	CAS Number	75873-85-7	Molecular Weight	632.74600
	Density	1.227g/cm3	Boiling Point	896.1ºC at 760 mmHg
	Molecular Formula	C₃₅H₄₄N₄O₇	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	495.8ºC
	Symbol	GHS08	Signal Word	Warning

Use of Z-Leu-Leu-Glu-βNA

Z-Leu-Leu-Glu-βNA (Z-Leu-Leu-Glu-β-naphthylamide) is a substrate for determination of the glutamylpeptidyl-peptide hydrolase activity of the 20S proteasome[1].

Name	N-CBZ-LEU-LEU-GLU β-NAPHTHYLAMIDE
Synonym	More Synonyms

Description	Z-Leu-Leu-Glu-βNA (Z-Leu-Leu-Glu-β-naphthylamide) is a substrate for determination of the glutamylpeptidyl-peptide hydrolase activity of the 20S proteasome[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
References	[1]. Reidlinger J, et al. Catalytic properties of 26 S and 20 S proteasomes and radiolabeling of MB1, LMP7, and C7 subunits associated with trypsin-like and chymotrypsin-like activities. J Biol Chem. 1997 Oct 3;272(40):24899-905.

Density	1.227g/cm3
Boiling Point	896.1ºC at 760 mmHg
Molecular Formula	C₃₅H₄₄N₄O₇
Molecular Weight	632.74600
Flash Point	495.8ºC
Exact Mass	632.32100
PSA	162.93000
LogP	6.24560
Index of Refraction	1.596

Z-Leu-Leu-Glu-βNA MSDS(Chinese)

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H351
Precautionary Statements	P281
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn
Risk Phrases	40
Safety Phrases	22-36
RIDADR	NONH for all modes of transport

Activation of GluR6-containing kainate receptors induces ubiquitin-dependent Bcl-2 degradation via denitrosylation in the rat hippocampus after kainate treatment.

J. Thorac. Cardiovasc. Surg. 286 , 7669-80, (2011)

We previously showed that Bcl-2 (B-cell lymphoma 2) is down-regulated in a kainate (KA)-induced rat epileptic seizure model. The underlying mechanism had remained largely unknown, but we here report f...

Evidence that pituitary cation-sensitive neutral endopeptidase is a multicatalytic protease complex.

J. Neurochem. 40 , 842-849, (1983)

Pituitary cation-sensitive neutral endopeptidase splits peptide bonds on the carboxyl side of hydrophobic amino acids (chymotrypsin-like activity), basic amino acids (trypsin-like activity), and acidi...

Characterization of recombinant REGalpha, REGbeta, and REGgamma proteasome activators.

J. Biol. Chem. 272 , 25483, (1997)

Full-length cDNAs for three human proteasome activator subunits, called REGalpha, REGbeta, and REGgamma, have been expressed in Escherichia coli, and the purified recombinant proteins have been charac...

N-cbz-leu-leu-glu B-naphthylamide

Z-LEU-LEU-GLU-BETANA

Z-Leu-Leu-Glu-bNA