BI-1915

Modify Date: 2025-08-25 13:03:55

BI-1915 Structure
BI-1915 structure
Common Name BI-1915
CAS Number 752237-67-5 Molecular Weight 407.559
Density N/A Boiling Point N/A
Molecular Formula C21H37N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BI-1915


BI-1915 (BI 1915) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 17 nM for in vitro use, no significant inhibition on Cathepsin L/K/B (IC50>10 uM);BI-1915 effectively blocks the specific ovalbumin induced IL-2 secretion in T-cells with an EC50 value of 2.8 nM.BI-1915 shows excellent selectivity against related cathepsins with IC50 values of >10 µM (Cat K and Cat B) and >30 µM (Cat L).

 Names

Name BI-1915

 BI-1915 Biological Activity

Description BI-1915 (BI 1915) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 17 nM for in vitro use, no significant inhibition on Cathepsin L/K/B (IC50>10 uM);BI-1915 effectively blocks the specific ovalbumin induced IL-2 secretion in T-cells with an EC50 value of 2.8 nM.BI-1915 shows excellent selectivity against related cathepsins with IC50 values of >10 µM (Cat K and Cat B) and >30 µM (Cat L).

 Chemical & Physical Properties

Molecular Formula C21H37N5O3
Molecular Weight 407.559
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