![]() BI-1915 structure
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Common Name | BI-1915 | ||
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CAS Number | 752237-67-5 | Molecular Weight | 407.559 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C21H37N5O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of BI-1915BI-1915 (BI 1915) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 17 nM for in vitro use, no significant inhibition on Cathepsin L/K/B (IC50>10 uM);BI-1915 effectively blocks the specific ovalbumin induced IL-2 secretion in T-cells with an EC50 value of 2.8 nM.BI-1915 shows excellent selectivity against related cathepsins with IC50 values of >10 µM (Cat K and Cat B) and >30 µM (Cat L). |
Name | BI-1915 |
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Description | BI-1915 (BI 1915) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 17 nM for in vitro use, no significant inhibition on Cathepsin L/K/B (IC50>10 uM);BI-1915 effectively blocks the specific ovalbumin induced IL-2 secretion in T-cells with an EC50 value of 2.8 nM.BI-1915 shows excellent selectivity against related cathepsins with IC50 values of >10 µM (Cat K and Cat B) and >30 µM (Cat L). |
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Molecular Formula | C21H37N5O3 |
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Molecular Weight | 407.559 |