1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione

Modify Date: 2025-09-27 16:04:24

1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione structure	Common Name	1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
	CAS Number	75191-50-3	Molecular Weight	255.27
	Density	1.311g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₇N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione

5’-Deoxy-5’-N-methylaminothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Synonym	More Synonyms

Description	5’-Deoxy-5’-N-methylaminothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.311g/cm3
Molecular Formula	C₁₁H₁₇N₃O₄
Molecular Weight	255.27
Exact Mass	255.12200
PSA	96.35000
Index of Refraction	1.555
InChIKey	SMLUVDLCTDSENP-UHFFFAOYSA-N
SMILES	CNCC1OC(n2cc(C)c(=O)[nH]c2=O)CC1O

Thymidine,5'-(4...

CAS#:7253-19-2

methylamine

CAS#:74-89-5

~96%

1-[4-hydroxy-5-...

CAS#:75191-50-3

Literature: Elliot; Brockman; Montgomery Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1052 - 1056

Thymidine

CAS#:50-89-5

1-[4-hydroxy-5-...

CAS#:75191-50-3

Literature: Idziak, Irene; Just, George; Damha, Masad J.; Giannaris, Paul A. Tetrahedron Letters, 1993 , vol. 34, # 34 p. 5417 - 5420

Precursor 3
CAS#:7253-19-2 Thymidine,5'-(4... CAS#:74-89-5 methylamine CAS#:50-89-5 Thymidine
DownStream 0

5'-methylamino-5'-deoxythimidine

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1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione

Use of 1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.