75191-50-3
75191-50-3 structure
- Name: 1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
- Chemical Name: 1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
- CAS Number: 75191-50-3
- Molecular Formula: C11H17N3O4
- Molecular Weight: 255.27
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-10-28 19:42:55
- Modify Date: 2024-01-09 19:01:23
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5’-Deoxy-5’-N-methylaminothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 1-[4-hydroxy-5-(methylaminomethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
|---|---|
| Synonyms | 5'-methylamino-5'-deoxythimidine |
| Description | 5’-Deoxy-5’-N-methylaminothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| References |
| Density | 1.311g/cm3 |
|---|---|
| Molecular Formula | C11H17N3O4 |
| Molecular Weight | 255.27 |
| Exact Mass | 255.12200 |
| PSA | 96.35000 |
| Index of Refraction | 1.555 |
|
~96%
75191-50-3 |
| Literature: Elliot; Brockman; Montgomery Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1052 - 1056 |
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~%
75191-50-3 |
| Literature: Idziak, Irene; Just, George; Damha, Masad J.; Giannaris, Paul A. Tetrahedron Letters, 1993 , vol. 34, # 34 p. 5417 - 5420 |
