Stromatoxin 1

Modify Date: 2024-01-13 07:22:18

Stromatoxin 1 Structure
Stromatoxin 1 structure
Common Name Stromatoxin 1
CAS Number 741738-59-0 Molecular Weight 3791.31
Density N/A Boiling Point N/A
Molecular Formula C156H237N49O48S7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Stromatoxin 1


Stromatoxin 1 is an inhibitor of Potassium Channel, a peptide which can be isolated from tarantulas. Stromatoxin 1 selectively inhibits K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3 channels. K(V)2.1 and K(V)2.2, but not K(V)4.2, channel subunits play a key role in opposing both myogenic and neurogenic urinary bladder smooth muscle (UBSM) contractions in rats[1].

 Names

Name Stromatoxin 1

 Stromatoxin 1 Biological Activity

Description Stromatoxin 1 is an inhibitor of Potassium Channel, a peptide which can be isolated from tarantulas. Stromatoxin 1 selectively inhibits K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3 channels. K(V)2.1 and K(V)2.2, but not K(V)4.2, channel subunits play a key role in opposing both myogenic and neurogenic urinary bladder smooth muscle (UBSM) contractions in rats[1].
Related Catalog
Target

K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3[1]

References

[1]. Chen M, et al. Voltage-gated K(+) channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle. Am J Physiol Regul Integr Comp Physiol. 2010 Jul;299(1):R177-84.  

 Chemical & Physical Properties

Molecular Formula C156H237N49O48S7
Molecular Weight 3791.31
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