4-Hydroxyphenyl-dimethyl-phenylsilan

Modify Date: 2024-02-27 18:09:02

4-Hydroxyphenyl-dimethyl-phenylsilan structure	Common Name	4-Hydroxyphenyl-dimethyl-phenylsilan
	CAS Number	74027-99-9	Molecular Weight	228.36200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₆OSi	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 4-Hydroxyphenyl-dimethyl-phenylsilan

Estrogen receptor-IN-1 (compound 16) is a potent estrogen receptor (ER) inhibitor with IC50s of 13, 5µM for ERα and Erβ, respectively[1].

Name	4-Hydroxyphenyl-dimethyl-phenylsilan
Synonym	More Synonyms

Description	Estrogen receptor-IN-1 (compound 16) is a potent estrogen receptor (ER) inhibitor with IC50s of 13, 5µM for ERα and Erβ, respectively[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Metabolic Disease
Target	ERα:13 μM (IC50) ERβ:5 μM (IC50)
References	[1]. Saito H, et al. Phosphine boranes as less hydrophobic building blocks than alkanes and silanes: Structure-property relationship and estrogen-receptor-modulating potency of 4-phosphinophenol derivatives. Bioorg Med Chem. 2020 Feb 15;28(4):115310.

Molecular Formula	C₁₄H₁₆OSi
Molecular Weight	228.36200
Exact Mass	228.09700
PSA	20.23000
LogP	2.21480

4-phenyldimethylsilylphenole

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